Document Detail

Pd-Catalyzed Tandem Cyclization of Ethyl Glyoxalate and Amines: Rapid Assembly of Highly Substituted Cyclic Dehydro-α-Amino Acid Derivatives.
MedLine Citation:
PMID:  23101491     Owner:  NLM     Status:  Publisher    
A novel cascade cyclization of ethyl glyoxalate and amines proceeds in the presence of Pd(TFA)(2) (5 mol %) to give the cyclic dehydro-α-amino acid derivatives. This method provides a fast and simple access to highly substituted dihydro-pyrrol-2-ones in good yields.
Yueting Luo; Xiaoxia Lu; Yong Ye; Ya Guo; Huanfeng Jiang; Wei Zeng
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-26
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
School of Chemistry and Chemical Engineering, South China University of Technology , No. 381, Wushan Road, Tianhe District, Guangzhou 510641, China, and Chengdu Institute of Biology, Academy of Sciences , Chengdu 610041, China.
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