Document Detail


Patulin in apple-based foods: occurrence and safety evaluation.
MedLine Citation:
PMID:  10945107     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Patulin is a mycotoxin produced by certain species of Penicillium and Aspergillus, often detectable in mouldy fruits and their derivatives. On the basis of a PMTDI of 0.4 microgram/kg bw, limit values of 50 micrograms/kg or 50 micrograms/l of patulin have been set in fruit derivatives. To estimate the quantity of patulin that can be taken in with the diet, we analysed by HPLC samples of apples and apple derivatives which are most likely to be contaminated with patulin. In apple juices and in homogenized baby-foods, the mycotoxin concentration was always below the established limits, while in some samples of juice with pulp the mycotoxin content exceeded the safe levels. In rotten apples, not only was the amount of patulin extraordinarily high in the rotten area, but the mycotoxin had also spread to the part unaffected by mould. The data presented in this study indicate that the intake of patulin with apple derivatives is usually below the tolerable level of 0.4 microgram/kg bw/day, but since the patulin content in apples can vary considerably, the quality of fruits used in the production of apple derivatives should be strictly controlled in order not to exceed the safe limits.
Authors:
B Beretta; A Gaiaschi; C L Galli; P Restani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food additives and contaminants     Volume:  17     ISSN:  0265-203X     ISO Abbreviation:  Food Addit Contam     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-08-31     Completed Date:  2000-08-31     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  8500474     Medline TA:  Food Addit Contam     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  399-406     Citation Subset:  IM    
Affiliation:
Laboratory of Toxicology, University of Milan, Italy.
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MeSH Terms
Descriptor/Qualifier:
Chromatography, High Pressure Liquid
Food Handling
Infant Food / analysis*
Mycotoxins / analysis
Patulin / analysis*
Rosales / chemistry*
Chemical
Reg. No./Substance:
0/Mycotoxins; 149-29-1/Patulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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