| Patterns of symptom reporting during pregnancy comparing opioid maintained and control women. | |
| | |
MedLine Citation:
|
PMID: 23135165 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: : To characterize the range of symptoms experienced by pregnant methadone-maintained (MM) and buprenorphine-maintained (BM) women to determine whether these differ from those experienced by a control group of nonopioid exposed pregnant women. Opioid-maintained (OM) patients report high rates of symptoms related to direct opioid effects and withdrawal. Pregnancy is associated with a range of symptoms, some overlapping with opioid effects and withdrawal. METHODS: : Prospective, nonrandomized, open-label comparison study undertaken in a large teaching maternity hospital in South Australia. Pregnant BM (n = 25), MM (n = 25) and nonopioid exposed controls (n = 25) were recruited and matched for age, parity, gravidity, alcohol consumption, and smoking status. Symptom report patterns, maternal withdrawal, and additional substance use were assessed. RESULTS: : MM women reported 10 and BM women reported 2 symptoms throughout pregnancy at rates greater than controls. Methadone-maintained women reported significantly (P < 0.05) more symptoms than BM women compared to controls throughout pregnancy. Methadone-maintained women reported 8 and BM women reported 3 symptoms in the third trimester at rates greater than controls. Methadone-maintained women reported greater opioid withdrawal than controls; this did not occur in BM women. Additional substance use was comparable between BM and MM women but greater than controls. CONCLUSIONS: : Patterns of symptom reports may have clinical implications for maternal and fetal health during pregnancy for OM women including optimization of opioid dosing regimens, education regarding maternal nutritional intake and preventing postnatal depression, thereby ensuring maternal health and fetal development during pregnancy and enhancing mother-infant bonding and healthy child development postnatally. |
| | |
Authors:
|
Andrea L Gordon; Olga V Lopatko; Helen Stacey; Vicki Pearson; Anna Woods; Ann Fisk; Jason M White |
Related Documents
:
|
20165935 - Risk of complication and revision total hip arthroplasty among medicare patients with d... 22486335 - A quantitative release assessment for the noncommercial movement of companion animals: ... 22541475 - Factors associated with cattle cleanliness on norwegian dairy farms. 23653955 - Efficacy of preparation solutions and cleansing techniques on contamination of the skin... 19086195 - Comparison of the body-worn cis-pro + and the behind-the-ear-worn tempo + cochlear impl... 2806485 - Adolescent childbearing and high school completion in the 1980s: have things changed? |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of addiction medicine Volume: 6 ISSN: 1932-0620 ISO Abbreviation: J Addict Med Publication Date: 2012 Dec |
Date Detail:
|
Created Date: 2012-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101306759 Medline TA: J Addict Med Country: United States |
Other Details:
|
Languages: eng Pagination: 258-64 Citation Subset: IM |
Affiliation:
|
From School of Nursing and Midwifery and School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, Division of Health Sciences, University of South Australia (ALG, JMW); Discipline of Pharmacology, University of Adelaide, Adelaide, Australia (ALG, OVL, JMW); Women's and Children's Hospital, Adelaide, Australia (HS); and Drug and Alcohol Services South Australia, Australia (VP, AF, AW). |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Modulation of feeding by chronic rAAV expression of a relaxin-3 peptide agonist in rat hypothalamus.
Next Document: Optimally efficient swimming in hyper-redundant mechanisms: control, design, and energy recovery.