Document Detail


Patterns and determinants of dyslipidaemia in 'Young' versus 'Not so Young' patients of coronary artery disease: a multicentric, randomised observational study in northern India.
MedLine Citation:
PMID:  22664802     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: The aims of the study were to ascertain difference in lipid levels of 'Young' onset of coronary artery disease (CAD) (≤ 45 years) vs. 'Not so Young' onset of CAD (≥ 55 years) among north Indians and also to investigate determinants of 'dyslipidaemia' in CAD patients.
METHODS: This was a prospective, multicentric, randomised, observational study carried in eight centres of UP, India. All blood investigations were performed employing a central laboratory.
RESULTS: Out of a total 435 patients studied, 218 were in the 'young group' (YG) and 235 were in the 'Not so Young Group' (NSYG). Dyslipidaemia was more common in YG as evident by significantly higher levels of total cholesterol, triglycerides, low- and very low-density lipoprotein cholesterol as compared to NSYG. Diabetes, hypertension, urban lifestyle, and family history of CAD were found to be important determinants of dyslipidaemia in YG.
CONCLUSION: We conclude that lipid levels among north Indians are significantly higher in younger patients with CAD when compared with elderly.
Authors:
Nakul Sinha; Sudeep Kumar; Himanshu Rai; Neha Singh; Aditya Kapoor; Satyendra Tewari; R K Saran; V S Narain; R P S Bharadwaj; R K Bansal; P C Saxena; P R Sinha; P R Gupta; Mukul Mishra; Praveen Jain; C M Pandey; Uttam Singh; S S Agarwal
Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indian heart journal     Volume:  64     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-06-05     Completed Date:  2013-08-27     Revised Date:  2014-03-28    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  India    
Other Details:
Languages:  eng     Pagination:  229-35     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Cohort Studies
Coronary Artery Disease / blood*,  complications*,  diagnosis
Dyslipidemias / blood,  diagnosis,  epidemiology*
Female
Humans
India
Male
Middle Aged
Random Allocation
Risk Factors
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