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Patterns of blood product use among patients with myelodysplastic syndrome.
MedLine Citation:
PMID:  22115321     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background and Objectives  Most patients with myelodysplastic syndrome (MDS) require blood product support to manage the severe anaemias, which frequently accompany MDS. Our objective was to show the feasibility of linking the Surveillance, Epidemiology and End Results (SEER) database with records from Puget Sound Blood Center (PSBC) to characterize blood product use over time in successive cohorts of patients with MDS. Materials and Methods  We identified patients with MDS in the SEER registry. The cohort was then linked to PSBC records to discern blood product use. Results  Included in the analysis were 783 patients with MDS entered in the SEER database from 2001 to 2007 for whom data were also available in the PSBC database. Among patients with MDS who received transfusions, 97% received packed red blood cells; 52% received platelets. The proportion of patients with MDS receiving blood products declined from 2001 to 2007. Conclusion  These data show a recent decline in blood product use for patients with MDS. Future studies are needed to further evaluate the reasons for this finding, specifically exploring the impact of newer medications on blood product use in patients with MDS.
Authors:
S D Ramsey; J S McCune; D K Blough; C L McDermott; S J Beck; J A López; H Joachim Deeg
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-24
Journal Detail:
Title:  Vox sanguinis     Volume:  -     ISSN:  1423-0410     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Author(s). Vox Sanguinis © 2011 International Society of Blood Transfusion.
Affiliation:
Research and Economic Assessment in Cancer and Healthcare (REACH) Group, Fred Hutchinson Cancer Research Center, Seattle, WA, USA School of Pharmacy, University of Washington, Seattle, WA, USA Puget Sound Blood Center, Seattle, WA, USA.
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