Document Detail


Patterns of alcohol consumption and fetal development.
MedLine Citation:
PMID:  6835605     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effects of heavy, moderate, and rare alcohol consumption on fetal development were analyzed in a prospective study of 469 mother-infant pairs. Differential effects of heavy drinking in early and late gestation were evaluated by separate analysis of neonates born to women who reduced consumption before the third trimester. Using chi 2 analysis, multiple regression, and matched sets, statistically significant associations (P less than .01) were observed between sustained heavy drinking and both intrauterine growth retardation and congenital anomalies. These associations were independent of eight other risk factors. No differences were observed between offspring of rare and moderate drinkers. Infants born to women who reduced heavy drinking did not differ in growth from offspring of rare and moderate drinkers but demonstrated a higher frequency of abnormalities. Sustained heavy drinking represents a major risk; reduction in midpregnancy can benefit the newborn. Identification and therapy of heavy drinking are important components of prenatal care.
Authors:
H L Rosett; L Weiner; A Lee; B Zuckerman; E Dooling; E Oppenheimer
Related Documents :
17204085 - Microgametophyte population sizes and plant reproductive output in the insect-pollinate...
9596275 - Prevalence of the partial molar phenotype in triploidy of maternal and paternal origin.
18644765 - Alcohol and substance use portrayals in nigerian video tapes: an analysis of 479 films ...
15938155 - Deaths from complications of unsafe abortion: misclassified second trimester deaths.
12099385 - Development of the hypothalamic-pituitary-adrenal axis in the fetus and preterm infant.
3353185 - Nursing interval and maternal responsivity: effect on early infant crying.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  61     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  539-46     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced / etiology*
Adult
Alcohol Drinking*
Female
Fetal Alcohol Syndrome / etiology*
Fetal Growth Retardation / etiology*
Humans
Pregnancy
Prenatal Exposure Delayed Effects*
Prospective Studies
Risk
Grant Support
ID/Acronym/Agency:
AA 07008/AA/NIAAA NIH HHS; R01-AAP2446/AA/NIAAA NIH HHS; TO1DA00031/DA/NIDA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A reinterpretation of schedule-induced behaviors based on a systematic analysis of behavior.
Next Document:  Practical use and efficiency of amniotic fluid OD 650 as a predictor of fetal pulmonary maturity.