| Patterns of antidepressant medication use among pregnant women in a United States population. | |
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MedLine Citation:
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PMID: 20663997 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This article describes the pattern of reported antidepressant use around the time of pregnancy in a population-based sample of women who delivered live-born babies without birth defects. Data were used from the National Birth Defects Prevention Study, an ongoing case-control study of risk factors for birth defects covering 10 US states. Mothers of live-born infants without birth defects (controls) born between 1998 and 2005 were randomly selected from each site. Information on the mother's characteristics and exposure to antidepressants was collected via a standardized telephone interview. Among 6582 mothers included in the study, 298 (4.5%) reported use of an antidepressant in the period of 3 months before through the end of pregnancy. Use of selective serotonin-reuptake inhibitors was reported most often (3.8%), followed by bupropion (0.7%). A statistically significant decline was observed, from 3.1% to 2.3% (P < .001), in reported use of antidepressants between the first and second month after conception. The frequency of reported antidepressant use at any time during pregnancy increased from 2.5% in 1998 to 8.1% in 2005 (P < .001) in 4 states. The findings show an increase in reported antidepressant use over a 9-year period and a substantial decrease in use around the usual time of pregnancy recognition. |
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Authors:
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Sura Alwan; Jennita Reefhuis; Sonja A Rasmussen; Jan M Friedman; |
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Publication Detail:
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Type: Journal Article Date: 2010-07-27 |
Journal Detail:
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Title: Journal of clinical pharmacology Volume: 51 ISSN: 1552-4604 ISO Abbreviation: J Clin Pharmacol Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0366372 Medline TA: J Clin Pharmacol Country: United States |
Other Details:
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Languages: eng Pagination: 264-70 Citation Subset: IM |
Affiliation:
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National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, GA 30333; e-mail: JReefhuis@cdc.gov. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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