Document Detail


Pattern of reactions in leprosy: a clinical appraisal.
MedLine Citation:
PMID:  198609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The term 'reactions' is applied in the present text, to describe the acute episodes, recognized with the different types of leprosy. The incidence of reactions was found to be 9.7% of 1053 cases examined. They were seen in all types of leprosy, but their frequency and severity was marked in lepromatous and borderline cases, and in majority of them, the age ranged from 20-40 years. The precipitating factor(s) could not be established in many; in some dapsone was incriminated, followed by bacterial infection and malnutrition. The exacerbations of the existing lesion(s) either alone or in combination with new lesions (E.N.L.) and E.N.L. lesions alone, were the presenting clinical features. The constitutional symptoms were observed largely in the types other than the tuberculoid. Foot drop and contractures of the fingers were the common sequels of the reactions. An attempt has been made to explain their mechanisms in the light of the recent literature.
Authors:
V N Sehgal; V L Rege; M F Mascarenhas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Leprosy in India     Volume:  49     ISSN:  0024-1024     ISO Abbreviation:  Lepr India     Publication Date:  1977 Apr 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376624     Medline TA:  Lepr India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  221-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Adult
Child
Dapsone / adverse effects,  therapeutic use
Edema / etiology
Erythema Nodosum / etiology
Female
Humans
Leprosy / complications*,  drug therapy
Male
Middle Aged
Peripheral Nervous System Diseases / etiology
Chemical
Reg. No./Substance:
80-08-0/Dapsone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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