Document Detail


Pattern of left ventricular diastolic filling associated with right ventricular enlargement.
MedLine Citation:
PMID:  2970779     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Right ventricular (RV) dilatation associated with pressure overload may alter left ventricular (LV) geometry resulting in abnormal diastolic function as demonstrated by a smaller LV diastolic volume for a given LV diastolic pressure. To determine whether abnormalities in LV geometry due to RV dilatation result in abnormalities in the LV diastolic filling pattern, we obtained pulsed Doppler transmitral recordings from 23 patients with RV dilatation with RV systolic pressure estimated to be less than 40 mm Hg (group 1), 18 patients with RV dilatation and RV systolic pressures greater than or equal to 40 mm Hg (group 2) and 33 normal patients. RV systolic pressures were estimated from continuous wave Doppler peak tricuspid regurgitation velocities using the modified Bernoulli equation. Diastolic filling parameters in group 1 patients were similar to normals. In group 2 patient, increased peak atrial filling velocity (76 +/- 14 vs 57 +/- 12 cm/s, p less than 0.001), decreased peak rapid filling velocity/peak atrial filling velocity (1.1 +/- 0.4 vs 1.5 +/- 0.4, p less than 0.01), increased atrial filling fraction (41 +/- 14 vs 30 +/- 10%, p less than 0.01) and prolongation of the atrial filling period (171 +/- 47 vs 152 +/- 39 ms, p less than 0.05) were noted compared with the normal group. RV end-diastolic size and LV end-systolic shape were significantly correlated with the atrial filling fraction in group 2 patients. In patients with RV dilatation and RV systolic pressures greater than or equal to 40 mm Hg, there is increased reliance on atrial systolic contribution to the LV filling volume.
Authors:
S J Lavine; L Tami; I Jawad
Related Documents :
10904039 - Effect of the mechanical ventilatory cycle on thermodilution right ventricular volumes ...
19644589 - Afterload- and preload-dependent interactions in the isolated biventricular working rat...
12424099 - Selective contractile dysfunction of left, not right, ventricular myocardium in the shh...
17607499 - Amino-terminal fragment of pro-brain natriuretic hormone identifies functional impairme...
14659859 - Assessment of the effects of various maneuvers on both atrial pressure changes.
7460199 - Pericardial modulation of right and left ventricular diastolic interaction.
3805119 - Late partial tamponade of the right atrium. a case report.
19337509 - Mechanisms of inhaled fine particulate air pollution-induced arterial blood pressure ch...
7485569 - Pressure wave propagation in a multibranched model of the human upper limb.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  62     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-09-30     Completed Date:  1988-09-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  444-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Harper Hospital, Wayne State University, Detroit, Michigan 48201.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity
Cardiomegaly / physiopathology*
Coronary Vessels / physiopathology*
Diastole
Dilatation, Pathologic
Echocardiography
Electrocardiography
Heart / physiopathology
Heart Ventricles / physiopathology
Humans
Middle Aged
Time Factors
Ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluation of age, gender, heart rate and blood pressure changes and exercise conditioning on Dopple...
Next Document:  Influence of enoximone and UDCG-115 on coronary hemodynamics in idiopathic dilated cardiomyopathy.