Document Detail

Pattern of intake of food additives associated with hyperactivity in Irish children and teenagers.
MedLine Citation:
PMID:  20013441     Owner:  NLM     Status:  MEDLINE    
A double-blind randomized intervention study has previously shown that a significant relationship exists between the consumption of various mixes of seven target additives by children and the onset of hyperactive behaviour. The present study set out to ascertain the pattern of intake of two mixes (A and B) of these seven target additives in Irish children and teenagers using the Irish national food consumption databases for children (n = 594) and teenagers (n = 441) and the National Food Ingredient Database. The majority of additive-containing foods consumed by both the children and teenagers contained one of the target additives. No food consumed by either the children or teenagers contained all seven of the target food additives. For each additive intake, estimates for every individual were made assuming that the additive was present at the maximum legal permitted level in those foods identified as containing it. For both groups, mean intakes of the food additives among consumers only were far below the doses used in the previous study on hyperactivity. Intakes at the 97.5th percentile of all food colours fell below the doses used in Mix B, while intakes for four of the six food colours were also below the doses used in Mix A. However, in the case of the preservative sodium benzoate, it exceeded the previously used dose in both children and teenagers. No child or teenager achieved the overall intakes used in the study linking food additives with hyperactivity.
A Connolly; A Hearty; A Nugent; A McKevitt; E Boylan; A Flynn; M J Gibney
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  27     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-17     Completed Date:  2010-06-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  England    
Other Details:
Languages:  eng     Pagination:  447-56     Citation Subset:  IM    
UCD Institute of Food & Health, UCD Agriculture & Food Science Centre, University College Dublin, Belfield, Dublin 4, Ireland.
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MeSH Terms
Attention Deficit Disorder with Hyperactivity / chemically induced*
Azo Compounds / administration & dosage,  adverse effects
Child, Preschool
Databases, Factual
Diet Surveys
Food / classification
Food Additives / adverse effects*
Food Labeling / legislation & jurisprudence
Naphthalenesulfonates / administration & dosage,  adverse effects
Quinolines / administration & dosage,  adverse effects
Risk Assessment
Tartrazine / administration & dosage,  adverse effects
Reg. No./Substance:
0/Azo Compounds; 0/Food Additives; 0/Naphthalenesulfonates; 0/Quinolines; 13613-55-3/azo rubin S; 1934-21-0/Tartrazine; 25956-17-6/Allura Red AC Dye; 2611-82-7/new coccine; 2783-94-0/FD & C Yellow No. 6; 8004-92-0/quinoline yellow

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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