Document Detail


Pattern of human blood spermidine and spermine in prematurity.
MedLine Citation:
PMID:  4039638     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood polyamines have been determined in preterm newborns (24-37 gestation weeks) during the first hours of life and until 20 days after birth. The most elevated polyamine concentrations were found in preterm newborns from the 24th-33rd gestational week. In all preterms, however, polyamine concentrations are higher than in full term newborns. In preterm infants two different patterns of blood polyamines appear in relation to the gestational age: in infants born at 24-34 wk, spermidine reaches the peak at 12 h and spermine shows high concentrations between 12 and 48 h. In infants born at 35-37 wk maximal concentrations of polyamines were reached at 12 h. Successively, in both groups the polyamines progressively decrease up to the 20th day, with some individual variations. Our results may provide a further support to the suggestion of a fetal genesis of polyamines and their involvement in fetal growth.
Authors:
A Casti; F Bacciottini; G Orlandini; N Reali; L Zannino; S Bernasconi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  147     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  1985 Apr 
Date Detail:
Created Date:  1985-07-11     Completed Date:  1985-07-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  223-32     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Infant, Newborn
Infant, Premature*
Male
Pregnancy
Spermidine / blood*
Spermine / blood*
Chemical
Reg. No./Substance:
124-20-9/Spermidine; 71-44-3/Spermine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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