Document Detail

Pattern of factor VIII inhibitors in patients with hemophilia A in the north east of Iran.
MedLine Citation:
PMID:  17325965     Owner:  NLM     Status:  MEDLINE    
This survey was conducted to evaluate coagulation factor VIII:C inhibitors among 102 hemophilia A patients from different cities of Khorasan province in north east of Iran in order to identify and characterize the pattern of inhibitor formation in these patients population. For this purpose, we randomly obtained plasma samples of 102 hemophilia A patients (44 patients with severe, 28 patients with intermediate and 30 patients with mild hemophilia A) and studied them using two tests: the APTT mix and Bethesda test were performed. In the whole group 20 patients (19.6%) factor VIII inhibitors were detected. These were in 11 patients with severe, five patients with intermediate and four patients with mild hemophilia A. None of patients with hemophilia A had previously been studied for the presence of an inhibitor, so there was no existing history of inhibitor evaluation.
A R Modaresi; H Mansouri Torghabeh; A A Pourfathollah; M Mahmoodian Shooshtari; Z Rezaie Yazdi
Related Documents :
9134635 - Long-term follow-up of hemostatic molecular markers during remission induction therapy ...
16988545 - A systematic review of antithrombin concentrate use in patients with disseminated intra...
20045995 - Registry of 919 patients with thrombotic microangiopathies across japan: database of na...
21510555 - Parvovirus b19 serology in early inflammatory polyarthritis--experience from a tertiary...
15376825 - What do we know? process analysis and the search for a better understanding of project ...
19458525 - Disability and functional profiles of patients with myasthenia gravis measured with icf...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hematology (Amsterdam, Netherlands)     Volume:  11     ISSN:  1607-8454     ISO Abbreviation:  Hematology     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2007-02-27     Completed Date:  2007-03-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708388     Medline TA:  Hematology     Country:  England    
Other Details:
Languages:  eng     Pagination:  215-7     Citation Subset:  IM    
Pediatric Hematology Group, Dr Sheikh Hospital, Mashad, Iran.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Antibody Specificity
Blood Coagulation Tests
Child, Preschool
Factor VIII / immunology*,  therapeutic use
Hemophilia A / epidemiology,  immunology*
Iran / epidemiology
Isoantibodies / biosynthesis,  immunology*
Middle Aged
Partial Thromboplastin Time
Sampling Studies
Reg. No./Substance:
0/Isoantibodies; 9001-27-8/Factor VIII

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Is time to treat for HCV all the HIV/HCV co-infected hemophiliacs?
Next Document:  Inhalation exposure systems: design, methods and operation.