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Pattern of cerebral ultrasound in neonatal heart surgery.
MedLine Citation:
PMID:  22145295     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
AIM: No study described reliably the changes in cerebral ultrasound (CUS) findings in neonatal heart surgery. We tried to define the modifications of CUS before and after heart surgery in neonates.
PATIENTS: We studied 48 neonates with congenital heart defects were studied. Of these, 33 had correction of the malformation with cardiopulmonary bypass (CPB group); 15 underwent coarctation repair/shunting procedures (no-CPB group). Patients had CUS pre-operatively, 48-72 hours after surgery, and at discharge.
RESULTS: Pre-operative studies did not show significant differences between the groups. In CPB group, preoperatively, 6/33 infants showed echogenicity of basal ganglia and 1/33 grade I IVH. In the early postoperative evaluation, 24/33 infants had abnormal scans: increased echogenicity of basal ganglia in 24 and grade I IVH in 14. At discharge, abnormal scans persisted in 20/33 (basal ganglia echogenicity in 20, grade I IVH in 12). In the no-CPB group, preoperatively, 1/15 infant showed echogenicity of basal ganglia. In the early postoperative evaluation, 6/15 had abnormal scans: increased echogenicity of basal ganglia in 6, grade I IVH in 4. At discharge, abnormal scans persisted in 3/15.
CONCLUSIONS: CUS after neonatal heart surgery shows a definite pattern of increased echogenicity of the basal ganglia, more consistent after CPB. These changes may reflect disturbances of deep grey matter, and last 10-15 days at least.
Authors:
L Rosti; A Giamberti; M Chessa; G Butera; G Pomè; M Braga; M Carminati; A Frigiola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  La Pediatria medica e chirurgica : Medical and surgical pediatrics     Volume:  33     ISSN:  0391-5387     ISO Abbreviation:  Pediatr Med Chir     Publication Date:    2011 May-Jun
Date Detail:
Created Date:  2011-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100625     Medline TA:  Pediatr Med Chir     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  124-8     Citation Subset:  IM    
Affiliation:
Department of Pediatric Cardiology and Heart Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Italy. luca.rosti@gmail.com
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