Document Detail

Patients with three or less dominant follicles may not be associated with reduced pregnancy rate of in vitro fertilization treatment.
MedLine Citation:
PMID:  16584831     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The management of poor ovarian responders remains a great challenge in in vitro fertilization (IVF) treatment. This study compared implantation and pregnancy rates among women who developed <or=3 dominant follicles of >or=16 mm in diameter and those who had >3 dominant follicles after ovarian stimulation. STUDY DESIGN: Retrospective study. RESULTS: Out of 911 consecutive patients receiving ovarian stimulation between January 2000 and December 2002, 894 (98.1%) patients underwent oocyte retrieval. Women with <or=3 dominant follicles were significantly older, required a longer duration and a higher dosage of gonadotrophin but produced lesser number of developing follicles, number of oocytes aspirated and number of embryos frozen when compared with those with >3 dominant follicles. Despite a significantly higher percentage of non-elective single embryo transfer in women with <or=3 dominant follicles, implantation rate, pregnancy rate and pregnancy outcomes were comparable for women with <or=3 and >3 dominant follicles. CONCLUSION: Implantation and pregnancy rates appeared to be comparable for women who developed <or=3 and >3 dominant follicles during IVF treatment.
Ernest H Y Ng; William S B Yeung; Pak C Ho
Publication Detail:
Type:  Journal Article     Date:  2006-04-11
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  129     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-30     Completed Date:  2007-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  54-9     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, PR China.
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MeSH Terms
Embryo Implantation*
Fertilization in Vitro / methods*
Follicle Stimulating Hormone / pharmacology
Ovarian Follicle / drug effects*
Ovulation Induction / methods*
Pregnancy Rate
Retrospective Studies
Reg. No./Substance:
9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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