Document Detail

Patients with multiple contact allergies: a review.
MedLine Citation:
PMID:  18154551     Owner:  NLM     Status:  MEDLINE    
Patients with multiple contact allergies, also referred to as polysensitized, are more frequent than predicted from prevalence of single sensitivities. The understanding of why some people develop multiple contact allergies, and characterization of patients with multiple contact allergies is limited. This review presents the current knowledge on the topic and discusses the evidence and characteristics of an increased susceptibility factor, possible causes to and genetic markers for the increased susceptibility, composition of the patient group and identification of patients at risk of developing multiple contact allergies. Evidence of allergen clusters among polysensitized individuals is also reviewed. The literature supports the idea that patients with multiple contact allergies constitute a special entity within the field of contact allergy. There is no generally accepted definition of patients with multiple contact allergies. We suggest that contact allergy to 3 or more allergens are defined as multiple contact allergies.
Berit Christina Carlsen; Klaus Ejner Andersen; Torkil Menné; Jeanne Duus Johansen
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Contact dermatitis     Volume:  58     ISSN:  1600-0536     ISO Abbreviation:  Contact Derm.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-24     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
National Allergy Research Centre, Department of Dermatology, Copenhagen University Hospital Gentofte, 2820 Gentofte, Denmark.
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MeSH Terms
Allergens / adverse effects*,  immunology
Cross Reactions
Dermatitis, Allergic Contact* / diagnosis,  epidemiology,  etiology,  immunology
Dinitrochlorobenzene / immunology
Disease Susceptibility
Eczema / complications,  epidemiology
Genetic Markers
Leg Ulcer / complications
Occupational Exposure / adverse effects
Patch Tests / methods
Risk Factors
Reg. No./Substance:
0/Allergens; 0/Genetic Markers; 97-00-7/Dinitrochlorobenzene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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