Document Detail

Patients with chronic hepatitis C undergoing watchful waiting: Exploring trajectories of illness uncertainty and fatigue.
MedLine Citation:
PMID:  20730869     Owner:  NLM     Status:  MEDLINE    
We identified trajectories of illness uncertainty in chronic hepatitis C patients and examined their association with fatigue levels during 12 months of disease monitoring without treatment (watchful waiting). Sixty-two men and 63 women completed uncertainty and fatigue measures. Groups were formed by uncertainty scores (high, medium, and low) at baseline. Baseline fatigue levels were higher in the high uncertainty group than in the medium and low groups. Over time, uncertainty levels did not change. Fatigue levels in the low uncertainty group remained constant, increased in the medium, and decreased in the high groups. Findings suggest that uncertainty and fatigue do not remit spontaneously. Being aware of this may help nurses identify those patients needing support for these two concerns.
Donald E Bailey; Julie Barroso; Andrew J Muir; Richard Sloane; Jacqui Richmond; John McHutchison; Keyur Patel; Lawrence Landerman; Merle H Mishel
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Research in nursing & health     Volume:  33     ISSN:  1098-240X     ISO Abbreviation:  Res Nurs Health     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2010-10-14     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  7806136     Medline TA:  Res Nurs Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  465-73     Citation Subset:  IM; N    
Copyright Information:
© 2010 Wiley Periodicals, Inc. Res Nurs Health 33:465-473, 2010.
Duke University School of Nursing, Durham, North Carolina.
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MeSH Terms
Adaptation, Psychological
Attitude to Health*
Fatigue / diagnosis,  epidemiology,  etiology,  psychology*
Follow-Up Studies
Hepatitis C, Chronic / psychology*
Middle Aged
Models, Statistical
Multivariate Analysis
Nursing Methodology Research
Risk Factors
Severity of Illness Index
Southeastern United States / epidemiology
Grant Support
1 R15 NR 008794-01A1/NR/NINR NIH HHS; R15 NR008704/NR/NINR NIH HHS

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