| Patients with Ulcerative Colitis Miss More Days of Work than the General Population, Even following Colectomy. | |
| | |
MedLine Citation:
|
PMID: 23232295 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND & AIMS:: It is unclear whether colectomy restores the ability of patients with ulcerative colitis (UC) to work to pre-colectomy levels. We estimated the burden of sick leave and disability pension in a population-based cohort of patients with UC and the effects of colectomy. METHODS:: We performed a register-based cohort study using the Swedish National Patient Register, and identified working-age patients with UC in 2005 (n=19,714) and patients that received colectomies between 1998 and 2002 (n=807). Sick leave and disability pension data were retrieved from Statistics Sweden (1995-2005). Data from each patient in the study were compared with those from 5 age-, sex-, education- and county-matched individuals from the general population. RESULTS:: In 2005, 15% of prevalent UC patients were on a disability pension, compared with 11% in the general population, and 21% vs 13% had =1 sick leave episode (P<.001 for each comparison). The annual median work days lost was 0 in both groups, but the UC patients had higher mean (65 vs 45 days; difference 20, 95% CI, 18-22 days) and 75th percentile work days lost (37 vs 0 days; difference 37, 95% CI, 36-38 days). Among patients that received colectomies, annual days lost increased from mean 40 (median 0) days 3 years before surgery to 141 (99) days during the surgery year (P<.001). The number then decreased to a mean of 85 days at 3 years after surgery (median 0). The corresponding 75th percentile days were 17, 207 and 130. Three years post colectomy, 12% did not work at all compared with 7.2% of the general population (risk difference 5.2%, 95% CI, 2.7%-7.7%), and compared with 5.9% 3 years before colectomy; P<.001. CONCLUSION:: Patients with UC miss more work days than the general population in Sweden. Although most patients had no registered work loss 3 years after colectomy, in the group that underwent colectomy, work loss was not restored to pre-surgery or general population levels during several years of follow-up. |
| | |
Authors:
|
Martin Neovius; Elizabeth V Arkema; Paul Blomqvist; Anders Ekbom; Karin E Smedby |
Related Documents
:
|
18181335 - Safety and efficacy of oral nifedipine versus terbutaline injection in preterm labor. 6691015 - Relationship of antepartum pelvic examinations to premature rupture of the membranes. 18455545 - Suture erosion rates and long-term surgical outcomes in patients undergoing sacrospinou... 23362835 - Therapeutic endoscopic retrograde cholangiography using a single-balloon enteroscope in... 21857545 - Is age a prognostic factor of postoperative outcome of lumbar disc herniation operations? 6189335 - Effect of betamethasone valerate on the normal human facial skin flora. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-12-8 |
Journal Detail:
|
Title: Gastroenterology Volume: - ISSN: 1528-0012 ISO Abbreviation: Gastroenterology Publication Date: 2012 Dec |
Date Detail:
|
Created Date: 2012-12-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0374630 Medline TA: Gastroenterology Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 AGA Institute. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Clinical Epidemiology Unit, Dept of Medicine Solna, Karolinska Institutet, Stockholm, Sweden. Electronic address: martin.neovius@ki.se. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A Dominant CD4+ T-Cell Response to Helicobacter pylori Reduces Risk for Gastric Disease in Humans.
Next Document: Transforming Growth Factor-b Signaling Controls Activities of Human Intestinal CD8+ T Suppressor Cel...