| Patients with Cushing's syndrome are care-intensive even in the era of laparoscopic adrenalectomy. | |
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MedLine Citation:
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PMID: 19385284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report outcomes from laparoscopic adrenalectomy (LA) comparing patients with Cushing's syndrome with those with other adrenal pathology with respect to length of stay (LOS), overall complications, and financial implications. We conducted a retrospective review of 80 continuous patients (103 glands) undergoing LA. The clinical diagnoses were: hypercortisolism (Cushing' syndrome; n=33), hyperaldosteronism (Conn's syndrome; n=20), phaeochromocytoma (n=16), and neoplasm (others; n=11). Advanced care in the intermediate or intensive care unit was necessary in 27 patients, most frequently in our Cushing's population (16 of 33 [48%]). Six patients sustained major complications, including death in two patients; seven patients sustained minor complications. LOS was longer for patients with Cushing's syndrome (mean, 5.5 vs. 3.3 days; P = 0.024). Financially, patients with Cushing's syndrome had statistically higher total hospital (P = 0.009), advanced care (P = 0.002), and anesthetic costs (P = 0.005). LA in patients with Cushing's syndrome is associated with longer hospitalizations, more frequent major complications, and higher advanced care requirements, especially for patients undergoing bilateral adrenalectomy. Minor complications were infrequent and median LOS was brief regardless of diagnosis. Patients with Cushing's syndrome had higher costs for overall hospital charges, advanced care, and anesthesia. |
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Authors:
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Nicole A Kissane; Juan C Cendan |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The American surgeon Volume: 75 ISSN: 0003-1348 ISO Abbreviation: Am Surg Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-23 Completed Date: 2009-05-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370522 Medline TA: Am Surg Country: United States |
Other Details:
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Languages: eng Pagination: 279-83 Citation Subset: IM |
Affiliation:
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Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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diagnosis,
surgery Adrenalectomy / methods* Adult Aged Cushing Syndrome / diagnosis, surgery* Diagnosis, Differential Female Follow-Up Studies Humans Hyperaldosteronism / diagnosis, surgery Intensive Care / methods* Laparoscopy / methods* Length of Stay / trends Male Middle Aged Pheochromocytoma / diagnosis, surgery Retrospective Studies Treatment Outcome Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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