Document Detail

Patients' preferences for intrauterine insemination or in-vitro fertilization.
MedLine Citation:
PMID:  17908405     Owner:  NLM     Status:  MEDLINE    
Patients' preferences for intrauterine insemination (IUI) relative to IVF were assessed using trade-off interviews, and the number of IUI cycles they would undergo before changing to IVF. A total of 73 couples undergoing IUI with a total of 111 interviews were included. Scenarios were offered where pregnancy chance after IUI was varied against a fixed pregnancy rate after IVF. The impact of multiple pregnancy risk on the couple's preference was also investigated. Interviews were held before starting IUI, after three or four IUI cycles and after six IUI cycles. With decreasing probability of ongoing pregnancy after IUI, an increasing number of couples switched their preference from IUI to IVF. This switch occurred after six cycles at a significantly higher (P = 0.01) mean cumulative pregnancy rate (53%) compared with other groups (31%). With increasing risk of multiple pregnancy, preference for IUI declined only slightly, with mean risks of 73, 78 and 83% of a multiple pregnancy for the three groups respectively. In conclusion, at baseline and after three cycles of IUI the majority of couples undergoing IUI preferred continuation of IUI over IVF. A clear shift in preference towards IVF occurred after six cycles. Risk of multiple pregnancy did not affect preference for IUI with ovarian stimulation.
Janne-Meije van Weert; Janneke van den Broek; Jan Willem van der Steeg; Fulco van der Veen; Paul A Flierman; Ben W J Mol; Pieternel Steures
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  15     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-02     Completed Date:  2007-12-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  422-7     Citation Subset:  IM    
Centre for Reproductive Medicine, Academic Medical Centre, Centre of Reproductive Medicine, Department of Obstetrics and Gynaecology, Amsterdam, The Netherlands.
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MeSH Terms
Fertilization in Vitro*
Insemination, Artificial, Homologous*
Patient Satisfaction*
Pregnancy Rate
Pregnancy, Multiple
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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