Document Detail


Patient with obstructive sleep apnea-hypopnea syndrome and SCN5A mutation (R1193Q polymorphism) associated with Brugada type 2 electrocardiographic pattern.
MedLine Citation:
PMID:  18976777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a 45-year-old Asian man with Brugada-type 2 electrocardiogram and probable nocturnal agonal respiration. After genetic screening, drug challenge test and polysomnography examination, we ruled out Brugada syndrome and identified obstructive sleep apnea-hypopnea syndrome. Therefore, obstructive sleep apnea-hypopnea syndrome should be considered as a rare differential diagnosis for Brugada syndrome.
Authors:
Xiaoliang Qiu; Wenling Liu; Dayi Hu; Yihong Sun; Lei Li; Cuilan Li
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-10-30
Journal Detail:
Title:  Journal of electrocardiology     Volume:  42     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2009 May-Jun
Date Detail:
Created Date:  2009-04-28     Completed Date:  2009-07-09     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  250-3     Citation Subset:  IM    
Affiliation:
Heart Center, Peking University People's Hospital, Beijing, PR China.
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MeSH Terms
Descriptor/Qualifier:
Brugada Syndrome / complications,  diagnosis*,  genetics*
Diagnosis, Differential
Electrocardiography / methods*
Genetic Predisposition to Disease / genetics
Humans
Male
Middle Aged
Mutation / genetics
Polymorphism, Single Nucleotide / genetics*
Sleep Apnea, Obstructive / complications,  diagnosis*,  genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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