Document Detail

A Patient with Relapsing Polychondritis who Had Been Diagnosed as Intractable Bronchial Asthma.
MedLine Citation:
PMID:  22790144     Owner:  NLM     Status:  In-Data-Review    
A 62-year-old woman, diagnosed as bronchial asthma 3 years previously, was admitted due to acute severe dyspnea. Physical examination revealed saddle nose, flare/swelling of the ear auricles, and stridor. Computed tomography demonstrated thickening of tracheal/bronchial walls and stenosis of the lumen that deteriorated on expiration, suggesting tracheobronchomalacia. Auricle biopsy indicated cartilage destruction. Based on these findings, the patient was diagnosed as relapsing polychondritis. As demonstrated in this case, relapsing polychondritis involving airways might be misdiagnosed as bronchial asthma due to stridor and transient corticosteroid-related improvement. Early diagnosis is necessary to prevent irreversible airway stenosis and progression to tracheobronchomalacia.
Ryota Sato; Nobuharu Ohshima; Kimihiko Masuda; Hirotoshi Matsui; Naoko Higaki; Eri Inoue; Jun Suzuki; Hideaki Nagai; Shinobu Akagawa; Akira Hebisawa; Shunsuke Shoji
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Publication Detail:
Type:  Journal Article     Date:  2012-07-01
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  51     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1773-8     Citation Subset:  IM    
Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan.
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