| Patient self-injection: a new approach to administering luteinizing hormone-releasing hormone analogues. | |
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MedLine Citation:
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PMID: 11069411 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the feasibility and advantages of self-injection of a depot dose of luteinizing hormone-releasing hormone (LHRH) analogue in patients with prostate cancer. PATIENTS AND METHODS: Twenty patients (mean age 70.9 years, range 53-85) with locally advanced or metastatic prostate cancer were recruited from urology clinics and, using a defined protocol, were taught to perform self-injection of a depot LHRH analogue (Prostap SR or Prostap 3, leuprorelin acetate, Wyeth Laboratories, Berks, UK). Patients were then followed for 1 year. RESULTS: Of the 20 patients, 11 successfully learned to use self-injection and administered injections for the duration of the study. Ten of the patients chose self-injection and continued to self-inject after the end of this study. CONCLUSIONS: This pilot study of 20 patients showed that it is feasible for a selected group of patients to be taught self-injection of an LHRH analogue, and that some patients prefer this mode of drug administration. |
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Authors:
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R Hamm; B Patel; T Whittlestone; R Persad |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: BJU international Volume: 86 ISSN: 1464-4096 ISO Abbreviation: BJU Int. Publication Date: 2000 Nov |
Date Detail:
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Created Date: 2001-01-10 Completed Date: 2001-02-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100886721 Medline TA: BJU Int Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 840-2 Citation Subset: IM |
Affiliation:
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Department of Urology, Derriford Hospital, Plymouth, UK. rebecca.hamm@virgin.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Feasibility Studies Gonadotropin-Releasing Hormone / administration & dosage*, analogs & derivatives* Humans Injections Male Middle Aged Pilot Projects Prostatic Neoplasms / drug therapy* Self Administration* |
| Chemical | |
Reg. No./Substance:
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33515-09-2/Gonadotropin-Releasing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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