Document Detail

Patient selection for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, and role of laparoscopy in diagnosis, staging, and treatment.
MedLine Citation:
PMID:  23021713     Owner:  NLM     Status:  In-Data-Review    
The indications for peritonectomy + hyperthermic intraperitoneal chemotherapy (HIPEC) are based on careful assessment of disease extent, but no imaging procedure is accurate enough to identify lesions smaller than 5 mm or extensively diffuse. Video-laparoscopy allows, with minimal surgical trauma, correct staging with a reliable prediction of expected cytoreduction index. Operative laparoscopy is indicated for palliation of neoplastic ascites with chemotherapy, offering encouraging results. Minimally invasive surgery in the treatment of minimal peritoneal carcinomatosis is not yet validated from wide international experience; the procedure is technically possible with strict indications, and combination with intraoperative hyperthermic chemotherapy is strongly recommended.
Mario Valle; Orietta Federici; Alfredo Garofalo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgical oncology clinics of North America     Volume:  21     ISSN:  1558-5042     ISO Abbreviation:  Surg. Oncol. Clin. N. Am.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211789     Medline TA:  Surg Oncol Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  515-31     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of GI Surgery, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome 00144, Italy.
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