Document Detail

Patient-controlled sedation with propofol in minor oral surgery.
MedLine Citation:
PMID:  14699549     Owner:  NLM     Status:  MEDLINE    
PURPOSE: We sought to evaluate the benefits of patient-controlled sedation with propofol for minor oral surgery. PATIENTS AND METHODS: After instructions were given on how to use the technique, 28 male and 24 female patients sedated themselves during minor oral surgery with titrating 18-mg bolus doses of propofol with a lockout period of 1 minute. RESULTS: Surgery lasted from 5 to 29 minutes; 28 patients were moderately and 17 were deeply sedated. Seven patients were oversedated. All of those who were oversedated responded to commands within 1 minute of being unresponsive and continued to obtain increments of propofol. Vital signs were stable in all patients even during oversedation. Eighteen patients were talkative, and 17 complained of pain along the vein. Operating conditions were good in 38, fair in 12, and poor in 2. The majority, 48 patients, were relaxed, and 47 were willing to undergo the sedation technique again. Ten had total, 22 had partial, and 20 had no amnesia. CONCLUSIONS: Relaxed patients, good operating conditions, and quick recovery of oversedated patients without unstable vital signs provide evidence that propofol has favorable pharmacokinetic and pharmacodynamic properties for patient-controlled sedation. This study also highlights the importance of close monitoring of patients during patient-controlled sedation.
Chandra Rodrigo; Michael G Irwin; Bill S W Yan; Man Hei Wong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons     Volume:  62     ISSN:  0278-2391     ISO Abbreviation:  J. Oral Maxillofac. Surg.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2003-12-30     Completed Date:  2004-02-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8206428     Medline TA:  J Oral Maxillofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  52-6     Citation Subset:  AIM; D; IM    
Department of Anaesthesiology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, People's Republic of China.
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MeSH Terms
Analgesia, Patient-Controlled*
Anesthesia Recovery Period
Anesthesia, Dental / methods*
Anesthetics, Intravenous / administration & dosage*
Conscious Sedation / methods
Oral Surgical Procedures / methods*
Propofol / administration & dosage*
Reg. No./Substance:
0/Anesthetics, Intravenous; 2078-54-8/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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