Document Detail


Patient age, refractive index of the corneal stroma, and outcomes of uneventful laser in situ keratomileusis.
MedLine Citation:
PMID:  23317777     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To determine the influence of age and the corneal stromal refractive index on the difference between the predicted and actual postoperative refractive error after laser in situ keratomileusis (LASIK) and whether the precision of outcomes could be improved by considering age and the refractive index. SETTING: Vissum Instituto Oftalmologico de Alicante, Alicante, Spain. DESIGN: Case series. METHODS: Flaps were created using a mechanical microkeratome. The stromal refractive index was measured using a VCH-1 refractometer after flap lifting. Refractive data were obtained 1, 3, and 6 months postoperatively. RESULTS: Uneventful LASIK was performed in 133 eyes. The mean age, refractive index, and applied corrections were 33.4 years ± 9.49 (SD), 1.368 ± 0.006, and -2.43 ± 3.36 diopters (D), respectively. The difference between the predicted and actual postoperative refractive error = 2.315-0.021 age-1.106 refractive index (F = 3.647, r = 0.254, P=.029; n = 109) at 1 month and = 11.820-0.023 age-7.976 refractive index (F = 3.392, r = 0.261, P=.022, n = 106) at 3 months. A correlation between the actual and calculated postoperative refraction improved from r = -0.178 (P=.064; n = 75) to r = -0.418 (P<.001) after considering the true refractive index 6 months postoperatively. CONCLUSIONS: The predicted outcomes of LASIK can be improved by inputting the refractive index of the individual corneal stroma. Unexpected outcomes (>0.50 D) of LASIK could be avoided by considering patient age and the refractive index and by adjusting the applied correction accordingly. FINANCIAL DISCLOSURE: Drs. Patel and Alió have a propriety interest in the VCH-1 refractometer used in this study. Both authors consulted on the design of the device by the manufacturers.
Authors:
Sudi Patel; Jorge L Alió; Anna Walewska; Francisco Amparo; Alberto Artola
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-11
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  -     ISSN:  1873-4502     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
Affiliation:
From Vissum Instituto Oftalmologico de Alicante, Alicante, Spain.
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