| Patient adherence to medication requirements for therapy of type 2 diabetes. | |
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MedLine Citation:
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PMID: 21314869 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Type 2 diabetes is a complex, progressive endocrine and metabolical disease that typically requires substantial lifestyle changes and multiple medications to lower blood glucose, reduce cardiovascular risk and address comorbidities. Despite an extensive range of available and effective treatments, < 50% of patients achieve a glycaemical target of HbA(1c) < 7.0% and about two-thirds die of premature cardiovascular disease. Adherence to prescribed therapies is an important factor in the management of type 2 diabetes that is often overlooked. Inadequate adherence to oral antidiabetes agents, defined as collecting < 80% of prescribed medication, is variously estimated to apply to between 36% and 93% of patients. All studies affirm that a significant proportion of type 2 diabetes patients exhibit poor adherence that will contribute to less than desired control. Identified factors that impede adherence include complex dosing regimens, clinical inertia, safety concerns, socioeconomic issues, ethnicity, patient education and beliefs, social support and polypharmacy. This review explores these factors and potential strategies to improve adherence in patients with type 2 diabetes. |
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Authors:
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C J Bailey; M Kodack |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of clinical practice Volume: 65 ISSN: 1742-1241 ISO Abbreviation: Int. J. Clin. Pract. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9712381 Medline TA: Int J Clin Pract Country: England |
Other Details:
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Languages: eng Pagination: 314-22 Citation Subset: IM |
Copyright Information:
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© 2011 Blackwell Publishing Ltd. |
Affiliation:
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School of Life and Health Sciences, Aston University, Birmingham, UK Medical Affairs, BlueSpark Healthcare Communications, Basking Ridge, NJ, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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