Document Detail

Pathophysiology and prevention of meconium aspiration syndrome.
MedLine Citation:
PMID:  7373268     Owner:  NLM     Status:  MEDLINE    
Aspiration of meconium by the fetus at or near delivery may be associated with high infant morbidity and mortality. The meconium aspiration syndrome (MAS) is often preventable, yet cases of MAS continue to occur. This paper describes the pathophysiology of MAS. The development of MAS involves passage of meconium by a compromised fetus and the subsequent aspiration of that meconium. Respiratory tract obstruction, hypoxia, hypercapnia, and acidosis may all result. Treatment of MAS is primarily supportive, and high mortality rates have been reported with the more severe cases. There is good evidence that careful suctioning of the infant's upper respiratory tract can in most cases prevent MAS. The suctioning, performed while the infant's head is still on the mother's perineum and prior to the first inspirations, is both a safe and effective preventive procedure.
L C Schussman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of family practice     Volume:  10     ISSN:  0094-3509     ISO Abbreviation:  J Fam Pract     Publication Date:  1980 Jun 
Date Detail:
Created Date:  1980-07-28     Completed Date:  1980-07-28     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7502590     Medline TA:  J Fam Pract     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  997-1002     Citation Subset:  AIM; IM    
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MeSH Terms
Airway Obstruction / etiology
Fetal Hypoxia / physiopathology
Fetus / physiology
Gastrointestinal Motility
Infant, Newborn
Pneumonia, Aspiration / complications,  physiopathology*,  prevention & control
Respiratory Insufficiency / etiology
Respiratory System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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