Document Detail

Pathophysiology, diagnosis, and management of dyslipidemia.
MedLine Citation:
PMID:  16824902     Owner:  NLM     Status:  MEDLINE    
Atherosclerosis is a systemic diffuse disease that may manifest as an anglographically localized coronary, cerebral, mesenteric, renal, and/or peripheral arterial stenosis or as diffuse atherosclerosis. While relief of organ ischemia is frequently possible with percutaneous or surgical revascularization, this in itself does not alleviate the long-term risks of disease recurrence or modify the metabolic derangements that promote atherosclerosis. It is critically important to recognize the need for treatment of dyslipidemia and to institute necessary therapies. The complex role of lipoprotein abnormalities is well understood and the use of lipid-lowering agents (90% statins) is reviewed in both primary and secondary prevention. The clinical interaction with novel risk factors and the practical problems in patient management are discussed.
Gerald T Gau; R Scott Wright
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  Current problems in cardiology     Volume:  31     ISSN:  0146-2806     ISO Abbreviation:  Curr Probl Cardiol     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-07     Completed Date:  2006-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7701802     Medline TA:  Curr Probl Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  445-86     Citation Subset:  IM    
Mayo College of Medicine, USA.
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MeSH Terms
Antilipemic Agents / therapeutic use*
Atherosclerosis / diagnosis,  etiology,  prevention & control
Biological Markers / blood
Cholesterol / blood*
Diagnosis, Differential
Disease Progression
Dyslipidemias* / diagnosis,  drug therapy,  physiopathology
Risk Factors
Reg. No./Substance:
0/Antilipemic Agents; 0/Biological Markers; 57-88-5/Cholesterol

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