| Pathophysiology of acute pancreatitis: evaluation of the effect and mode of action of steroids in experimental pancreatitis in dogs. | |
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MedLine Citation:
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PMID: 7091513 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three experiments were performed to evaluate the effects and hemodynamic changes brought about by steroids in experimental pancreatitis in dogs. The results show (1) a significant improval in survival in steroid-treated groups, (2) no difference in cardiac output or mean blood pressure between groups, (3) a decrease in relative pancreatic arterial blood flow in the untreated animals, and (4) an increase in arterial flow to the pancreas after steroid therapy. The experiments suggest that the reversal of reduced pancreatic flow may be important in improving the prognosis. |
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Authors:
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J G Studley; W G Schenk |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of surgery Volume: 143 ISSN: 0002-9610 ISO Abbreviation: Am. J. Surg. Publication Date: 1982 Jun |
Date Detail:
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Created Date: 1982-08-07 Completed Date: 1982-08-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370473 Medline TA: Am J Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 761-4 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Animals Blood Circulation / drug effects Blood Pressure / drug effects Cardiac Output / drug effects Dogs Hydrocortisone / pharmacology, therapeutic use Pancreatitis / drug therapy, physiopathology* |
| Grant Support | |
ID/Acronym/Agency:
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AM-26186/AM/NIADDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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