Document Detail

Pathophysiology of laparoscopic adjustable gastric bands: analysis and classification using high-resolution video manometry and a stress barium protocol.
MedLine Citation:
PMID:  19763707     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Symmetrical pouch dilatation has become the most common problem following laparoscopic adjustable gastric banding (LAGB). Although, in a significant number of symptomatic patients, no explanation for the underlying problem is identified with a contrast swallow. There is a need for a better understanding of the pathophysiology of LAGBs and more sensitive diagnostic tests. METHODS: LAGB patients with adverse symptoms or poor weight loss (symptomatic patients), in whom a contrast swallow had not shown an abnormality, underwent high-resolution video manometry. This incorporated a semi-solid, stress barium, swallow protocol. Outcomes were categorized based on anatomical appearance, transit through the LAGB, and esophageal motility. Cohorts of successful (>50% excess weight loss with no adverse symptoms) and pre-operative patients were used as controls. RESULTS: One hundred twenty-three symptomatic patients participated along with 30 successful and 56 pre-operative patients. Five pathophysiological patterns were defined: transhiatal enlargement (n = 40), sub-diaphragmatic enlargement (n = 39), no abnormality (n = 30), aperistaltic esophagus (n = 7), and intermittent gastric prolapse (n = 3). Esophageal motility disorders were more common in symptomatic and pre-operative patients than in successful patients (p = 0.01). Differences between successful and symptomatic patients were identified in terms of the length of the high-pressure zone above the LAGB (p < 0.005), peristaltic velocity (p < 0.005), frequency of previous surgery(p = 0.01), and lower esophageal sphincter tone (p = 0.05). CONCLUSIONS: Video manometry identified abnormalities in three quarters of symptomatic patients where conventional contrast swallow had not been diagnostic. Five primary patterns of pathophysiology were defined. These were used to develop a seven category, clinical, classification system based on the anatomical appearance at stress barium. This system stratifies the spectrum of symmetrical pouch dilatation and can be used to logically guide treatment.
Paul Robert Burton; Wendy A Brown; Cheryl Laurie; Anna Korin; Kenneth Yap; Melissa Richards; John Owens; Gary Crosthwaite; Geoff Hebbard; Paul E O'Brien
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Publication Detail:
Type:  Journal Article     Date:  2009-09-18
Journal Detail:
Title:  Obesity surgery     Volume:  20     ISSN:  1708-0428     ISO Abbreviation:  Obes Surg     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-04-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106714     Medline TA:  Obes Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  19-29     Citation Subset:  IM    
Centre for Obesity Research and Education, Monash University, Melbourne, Australia.
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MeSH Terms
Barium Sulfate / diagnostic use
Dilatation, Pathologic
Esophageal Motility Disorders / epidemiology,  physiopathology
Esophageal Sphincter, Lower / physiopathology
Gastroplasty* / adverse effects,  methods
Middle Aged
Obesity, Morbid / epidemiology,  physiopathology,  surgery
Postoperative Complications / physiopathology
Video Recording
Reg. No./Substance:
7727-43-7/Barium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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