Document Detail


Pathophysiology of increased fetal nuchal translucency thickness.
MedLine Citation:
PMID:  20708516     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Increased fetal nuchal translucency thickness is associated with trisomy 13, trisomy 18, trisomy 21, Turner syndrome, other sex chromosome abnormalities, as well as many fetal anomalies and genetic syndromes. This article provides a comprehensive review of the cardinal proposed pathophysiology including altered composition of the extracellular matrix, abnormalities of the heart and great arteries, and disturbed or delayed lymphatic development.
Authors:
Chih-Ping Chen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Taiwanese journal of obstetrics & gynecology     Volume:  49     ISSN:  1875-6263     ISO Abbreviation:  Taiwan J Obstet Gynecol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-08-16     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101213819     Medline TA:  Taiwan J Obstet Gynecol     Country:  China    
Other Details:
Languages:  eng     Pagination:  133-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Taiwan Association of Obstetrics and Gynecology. Published by Elsevier B.V. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan. cpc_mmh@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Extracellular Matrix / metabolism*,  pathology
Extracellular Matrix Proteins / metabolism
Female
Heart Defects, Congenital / physiopathology
Humans
Lymphatic System / abnormalities
Nuchal Translucency Measurement*
Pregnancy
Skin / metabolism
Trisomy / diagnosis,  physiopathology
Turner Syndrome / diagnosis,  physiopathology
Chemical
Reg. No./Substance:
0/Extracellular Matrix Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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