| Pathophysiology of GERD in China: the same factors at a lower scale. | |
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MedLine Citation:
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PMID: 15554986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most of the factors involved in the pathogenesis of gastroesophageal reflux disease (GERD), previously described in European, Australian, and American studies, are present in Chinese patients with GERD, but at a lower scale. The acidity of gastric contents is reduced either spontaneously or by Helicobater pylori infection. A low-fat diet probably contributes to a more favorable gastric distribution of the meals, reduced obesity, and lowers the number of TLESRs. The prevalence of hiatal hernia is low and esophageal motility disorders are moderate. Like in Western countries, the pathophysiology of GERD in China is multifactorial, with variable combination of moderate abnormalities in individual patients, leading to milder forms of GERD. |
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Authors:
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Daniel Sifrim; Xin Zhang |
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Publication Detail:
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Type: Comment; Editorial |
Journal Detail:
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Title: The American journal of gastroenterology Volume: 99 ISSN: 0002-9270 ISO Abbreviation: Am. J. Gastroenterol. Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-11-23 Completed Date: 2004-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0421030 Medline TA: Am J Gastroenterol Country: United States |
Other Details:
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Languages: eng Pagination: 2094-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asian Continental Ancestry Group* Esophagus / physiopathology Gastroesophageal Reflux / ethnology*, etiology, physiopathology Humans Hydrogen-Ion Concentration Peristalsis Risk Factors |
| Comments/Corrections | |
Comment On:
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Am J Gastroenterol. 2004 Nov;99(11):2088-93
[PMID:
15554985
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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