| Pathophysiological role of cytokines in congestive heart failure. | |
| | |
MedLine Citation:
|
PMID: 11160765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Heart failure is a complex neurohumoral and inflammatory syndrome. Recent studies have shown that proinflammatory cytokines (interleukin-1, interleukin-2, interleukin-6, interleukin-10, and tumor necrosis factor) are involved in cardiac depression and in the complex syndrome of heart failure. Understanding the involvement of these cytokines may enable us to reverse cardiac depression and heart failure by the use of monoclonal antibodies directed against specific cytokines to block the downhill progression of heart failure. |
| | |
Authors:
|
A Blum; H Miller |
Related Documents
:
|
16272775 - Decreased heart rate recovery in patients with heart failure: effect of fluvastatin the... 9140785 - How common is heart failure due to systemic hypertension alone in hospitalised nigerians? 17884075 - Importance of electrocardiography in the assessment and management of heart failure: a ... 12193525 - Clinical course and medical management of neonates with severe cardiac failure related ... 11557745 - Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remod... 18318925 - The teleguard trial of additional telemedicine care in cad patients. 2 morbidity and mo... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Annual review of medicine Volume: 52 ISSN: 0066-4219 ISO Abbreviation: Annu. Rev. Med. Publication Date: 2001 |
Date Detail:
|
Created Date: 2001-02-22 Completed Date: 2001-04-26 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 2985151R Medline TA: Annu Rev Med Country: United States |
Other Details:
|
Languages: eng Pagination: 15-27 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine, Poria Hospital, Lower Galilee 15208, Israel. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antibodies, Monoclonal
/
therapeutic use Autonomic Nervous System / physiopathology Cytokines / antagonists & inhibitors, blood, immunology* Disease Models, Animal Disease Progression Heart Failure / blood, immunology*, physiopathology*, therapy Humans Inflammation Interleukin-1 / antagonists & inhibitors, immunology* Interleukin-10 / antagonists & inhibitors, immunology* Interleukin-2 / antagonists & inhibitors, immunology* Interleukin-6 / antagonists & inhibitors, immunology* Neurotransmitter Agents / physiology Tumor Necrosis Factor-alpha / antagonists & inhibitors, immunology* |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies, Monoclonal; 0/Cytokines; 0/Interleukin-1; 0/Interleukin-2; 0/Interleukin-6; 0/Neurotransmitter Agents; 0/Tumor Necrosis Factor-alpha; 130068-27-8/Interleukin-10 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Regulation of leukotrienes in the management of asthma: biology and clinical therapy.
Next Document: Current treatment strategies for chronic hepatitis B and C.