Document Detail


Pathophysiological and clinical approach to cirrhotic cardiomyopathy.
MedLine Citation:
PMID:  25267959     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hyperdynamic circulation, systolic and diastolic left ventricular dysfunction and certain electrophysiological abnormalities have been associated with cirrhosis and known for a long time. These clinical features have been introduced as cirrhotic cardiomyopathy (CCM), which is characterized by blunted myocardial contractile responsiveness to physical, physiological and pharmacological stress. Importantly, cardiac dysfunction can be reversible and can improve due to effective medical treatment and also after liver transplantation. Echocardiography and electrocardiography are essential tools for recognizing the characteristic changes in the myocardial function and also the alterations in the electrophysiological properties of the heart. Laboratory markers are auxiliary modalities further aiding the establishment of the correct diagnosis. In this review, we aimed to collect the pathophysiological background and clinical characteristics of CCM with the intention of summarizing the current possibilities for the diagnosis establishment and treatment of this cardio-hepatic disorder.
Authors:
Alida Páll; Arpád Czifra; Zsuzsanna Vitális; Mária Papp; György Paragh; Zoltán Szabó
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Publication Detail:
Type:  REVIEW    
Journal Detail:
Title:  Journal of gastrointestinal and liver diseases : JGLD     Volume:  23     ISSN:  1842-1121     ISO Abbreviation:  J Gastrointestin Liver Dis     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-30     Completed Date:  -     Revised Date:  2014-10-1    
Medline Journal Info:
Nlm Unique ID:  101272825     Medline TA:  J Gastrointestin Liver Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  301-310     Citation Subset:  -    
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