Document Detail

Pathophysiological aspects of hypertensive disease in women.
MedLine Citation:
PMID:  12183855     Owner:  NLM     Status:  MEDLINE    
Although during the past two decades there has been considerable progress in the understanding of the pathophysiology of human essential hypertension, the basic mechanisms responsible for the development and progression of the disease still remain largely undefined. This also applies to the pathophysiology of hypertension in women, although a number of haemodynamic, vascular, metabolic and neurohumoral factors have been identified throughout the years as being characterized by a gender-specific relation. This paper will examine the main differences in the haemodynamic, vascular, metabolic and neurohumoral profile characterizing normotensive as well as hypertensive females as compared with age-matched males. Although in some instances clearcut differences between genders can be found, overall the pathophysiological picture of the hypertensive state does not seem to have significant differences in men and women, at least up to the years when the menopausal-related hormonal changes take place.
Guido Grassi; Gino Seravalle; Maria Luisa Stella; Giuseppe Mancia
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of hypertension. Supplement : official journal of the International Society of Hypertension     Volume:  20     ISSN:  0952-1178     ISO Abbreviation:  J Hypertens Suppl     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-08-19     Completed Date:  2003-01-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8501422     Medline TA:  J Hypertens Suppl     Country:  England    
Other Details:
Languages:  eng     Pagination:  S6-10     Citation Subset:  IM    
Università Milano-Bicocca, Ospedale San Gerardo, Istituto Auxologico Italiano, Centro di Fisiologia Clinica ed Ipertensione, Milan, Italy.
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MeSH Terms
Evidence-Based Medicine
Hypertension / metabolism,  physiopathology*
Sex Factors
Women's Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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