Document Detail

Pathophysiologic bases for adjunctive therapies in the treatment and secondary prevention of acute myocardial infarction.
MedLine Citation:
PMID:  9541759     Owner:  NLM     Status:  MEDLINE    
Postmyocardial infarction (MI) survival has been steadily improving. This improvement has been due, in part, to the actions of the adjunctive medical therapies for the treatment of MI. Aspirin, beta blockers, angiotensin-converting enzyme (ACE) inhibitors, and lipid-lowering agents have been shown to improve survival in the treatment and secondary prevention of MI. Nitrates have beneficial effects as well. These medications complement the reperfusion strategies through different mechanisms. Other adjunctive medical therapies, namely magnesium, antiarrhythmic agents, and calcium-channel blockers, have not been shown to improve mortality with routine post-MI use despite their theoretical benefits.
D E Gutstein; V Fuster
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  21     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-05-21     Completed Date:  1998-05-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  161-8     Citation Subset:  IM    
Cardiovascular Institute, Mount Sinai Medical Center, New York, New York 10029-6574, USA.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Anti-Arrhythmia Agents / therapeutic use
Anticoagulants / therapeutic use
Antilipemic Agents / therapeutic use
Aspirin / therapeutic use
Calcium Channel Blockers / therapeutic use
Cyclooxygenase Inhibitors / therapeutic use
Magnesium / therapeutic use
Myocardial Infarction / drug therapy*,  physiopathology,  prevention & control
Vasodilator Agents / therapeutic use
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Anti-Arrhythmia Agents; 0/Anticoagulants; 0/Antilipemic Agents; 0/Calcium Channel Blockers; 0/Cyclooxygenase Inhibitors; 0/Vasodilator Agents; 50-78-2/Aspirin; 7439-95-4/Magnesium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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