Document Detail


Pathomorphological criteria for cardiosclerosis and angioarchitectonics of the hypertrophic myocardium in hypertensive heart.
MedLine Citation:
PMID:  15452614     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed a pathomorphological study of 200 hearts with cicatricial changes from patients died from hypertensive disease. Most postinfarction scars in men were transmural and localized in the anterior and posterior wall of the left ventricle and in the interventricular septum. Non-transmural scars were revealed in the lateral wall (primarily in women). Pathognomonic changes in the architectonics of the heart included reduction of regional blood flow and segmentary, discontinuously extended, and diffusely extended atherosclerotic obstruction. Changes in the index of blood supply to the myocardium corresponded to pronounced decrease in vascularization of the hypertrophic left ventricle. A correlation was found between the index of blood supply to the myocardium and mean systolic and diastolic blood pressure. Therefore, the coronary bed did not satisfy the demands of hypertensive heart with cicatricial changes.
Authors:
V D Rozenberg; L M Nepomnyashchikh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  137     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-09-28     Completed Date:  2005-02-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  398-402     Citation Subset:  IM    
Affiliation:
Department of General Pathology and Pathomorphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure
Coronary Circulation*
Female
Humans
Hypertension / pathology*
Hypertrophy*
Male
Middle Aged
Myocardial Ischemia
Myocardium / pathology*
Regional Blood Flow

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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