| Pathomorphological characteristics of experimental toxemia induced by thermostable Yersinia pseudotuberculosis toxin. | |
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MedLine Citation:
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PMID: 11182834 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pathogenic properties of thermostable toxin responsible for pathogenicity of Yersinia pseudotuberculosis were experimentally studied. The toxin exerted a pronounced polyorgan cytopathogenic effect with predominating degenerative destructive changes and membranolytic effect on cell ultrastructure of parenchymatous organs. The toxin is believed to be directly involved in the development of typical pathomorphological picture of pseudotuberculosis, which confirms its pathogenetic role. |
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Authors:
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L M Isachkova; N F Timchenko; E P Nedashkovskaya; S D Raznik |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 130 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2000 Nov |
Date Detail:
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Created Date: 2001-02-22 Completed Date: 2001-09-06 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 1123-6 Citation Subset: IM |
Affiliation:
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Institute of Epidemiology and Microbiology, Siberian Division, Russian Academy of Medical Sciences, Vladivostok, Russia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bacterial Toxins / administration & dosage, toxicity* Capillaries / drug effects, pathology Disease Models, Animal Enterotoxins / administration & dosage, toxicity* Gallbladder / drug effects, pathology Heart / drug effects Kidney / drug effects, pathology Liver / drug effects, pathology Lung / drug effects, pathology Mice Myocardium / pathology Spleen / drug effects, pathology Toxemia / pathology* Yersinia pseudotuberculosis* |
| Chemical | |
Reg. No./Substance:
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0/Bacterial Toxins; 0/Enterotoxins; 0/heat-stable enterotoxin (Yersinia) |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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