| Pathology of small cerebral arteries demonstrated by MRI: a marker of aging? | |
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MedLine Citation:
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PMID: 22182824 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Brain magnetic resonance imaging frequently identifies signal abnormalities in the white matter and cerebral cortex in the elderly. They are related to a degenerative disease of the small vessels that may be of ischemic (leukoaraiosis, lacunae and infarct) or hemorrhagic (microbleeds and hematomas) origin. These lesions are part of the aging process, and compounded by vascular risk factors. They increase the occurrence frequency and severity of ischemic or hemorrhagic stroke. Their importance is also associated with the presence of cognitive and/or affective symptoms, and their impact on the occurrence and evolution of dementia remains to be evaluated. The visible consequences of this microangiopathy on MRI probably represent the focal mark of a widespread cerebrovascular disease in the brain parenchyma. |
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Authors:
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Jean-Philippe Cottier; Myriam Edjlali; Marie-Agnès Gaillard; Florence Domengie; Ali Aljishi; Xavier Casals; Denis Herbreteau; Caroline Hommet |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Geriatrie et psychologie neuropsychiatrie du vieillissement Volume: 9 ISSN: 2115-8789 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101553404 Medline TA: Geriatr Psychol Neuropsychiatr Vieil Country: - |
Other Details:
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Languages: ENG Pagination: 465-475 Citation Subset: - |
Affiliation:
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Service de neuroradiologie, CHRU de Tours, UMR Inserm U 930, Tours, Université François Rabelais, Tours. |
Vernacular Title:
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Pathologie des petites artères cérébrales mise en évidence par l'IRM : un marqueur du vieillissement ? |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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