| Pathology of pituitary adenomas. | |
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MedLine Citation:
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PMID: 227505 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A new pituitary classification has been developed, based on the histologic, histochemical, immunocytologic and electron microscopic investigation of 207 pituitary adenomas removed surgically from male and female patients of various ages and different clinical symptomatology. Based principally on cytogenesis, the classification attempts to correlate the morphologic features of the tumor cells with their secretory activities, the clinical history, symptomatology, and biochemical findings. The classification consists of the following eight entities: 1) growth hormone cell adenoma; 2) prolactin cell adenoma; 3) mixed growth hormone cell-prolactin cell adenoma; 4) acidophil stem cell adenoma; 5) corticotroph cell adenoma; 6) thyrotroph cell adenoma; 7) gonadotroph cell adenoma; 8) undifferentiated cell adenoma, including oncocytoma. Prolactin adenomas were found to be the most frequently occurring pituitary adenoma type. |
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Authors:
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K Kovacs; E Horvath |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Bulletin of the Los Angeles neurological societies Volume: 42 ISSN: 0024-659X ISO Abbreviation: Bull Los Angeles Neurol Soc Publication Date: 1977 |
Date Detail:
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Created Date: 1980-01-19 Completed Date: 1980-01-19 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0064572 Medline TA: Bull Los Angeles Neurol Soc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 92-110 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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ultrastructure* Adenoma, Acidophil / ultrastructure Adenoma, Basophil / ultrastructure Adenoma, Chromophobe / ultrastructure Adrenocorticotropic Hormone / blood Follicle Stimulating Hormone / blood Growth Hormone / blood Humans Immunoenzyme Techniques Luteinizing Hormone / blood Paraneoplastic Endocrine Syndromes / ultrastructure Pituitary Gland / ultrastructure Pituitary Neoplasms / ultrastructure* Prolactin / blood Thyrotropin / blood |
| Chemical | |
Reg. No./Substance:
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9002-60-2/Adrenocorticotropic Hormone; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone; 9002-71-5/Thyrotropin; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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