Document Detail


Pathology and pathophysiology of cerebrovascular dementia: pure subgroups of obstructive and hypoperfusive etiology.
MedLine Citation:
PMID:  8087169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The brains of 175 consecutive autopsy cases of dementia, clinically studied prospectively, were analyzed pathoanatomically with regard to type, size and site of lesions. Pure groups of vascular dementia caused by large or small vessel disease and by hypoperfusion could be defined. The infarcts were either complete with a more or less pronounced incomplete perifocal component or of an incomplete type only. Incomplete infarction appears to be an important and yet little appreciated cause of brain dysfunction. These groups could be used as a basis for a pathoanatomical classification of vascular dementias. Vascular dementia is much more common than generally assumed.
Authors:
A Brun
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Dementia (Basel, Switzerland)     Volume:  5     ISSN:  1013-7424     ISO Abbreviation:  Dementia     Publication Date:    1994 May-Aug
Date Detail:
Created Date:  1994-10-20     Completed Date:  1994-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9010348     Medline TA:  Dementia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  145-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, University of Lund, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Cerebrovascular Circulation / physiology
Cerebrovascular Disorders / etiology,  pathology*,  physiopathology*
Dementia, Vascular / etiology,  pathology*,  physiopathology*
Humans
Middle Aged
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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