| Pathology of malignant melanoma of the skin in Black Africans. | |
| | |
MedLine Citation:
|
PMID: 1138394 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Follow-up data (over a 3-year period) and the histological appearances of primary lesion were studied and related in 40 Black patients with malignant melanoma. This to our knowledge is the first study in Black African patients. It was found that they present with large deeply invasive lesions, particularly on the foot. The prognosis is poor, with an over-all 3-year survival rate of 35%. The histological features used to assess the prognosis of malignant melanoma in Whites, that is histogenetic pattern, size and shape of the lesion, level of invasion, presence of ulceration and mitotic activity would seem to be equally applicable in Black patients. In addition, marked cellular pleomorphism, haemorrhage, necrosis and fibrosis within the tumour are bad signs. In this series lymphocytic infiltration, either within the tumour or at the edge, possibly indicative of an immune response, seemed to be of favourable prognostic import. Surprisingly, a lesion histologica-ly that of lentigo maligna melanoma was found on the feer of some blacks and could be related to much more favourable survival figures. |
| | |
Authors:
|
J J Rippey; E Rippey; R M Giraud |
Related Documents
:
|
3100744 - Neurotropic melanoma of the lower lip. 12411994 - Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma. 16255424 - Fractal characterisation of boundary irregularity in skin pigmented lesions. 4047734 - The dysplastic nevus. 23257724 - Development and evaluation of nucleic acid-based techniques for an auxiliary diagnosis ... 19461404 - Spontaneous pneumothorax and lung carcinoma: should one consider synchronous malignant ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 49 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 1975 May |
Date Detail:
|
Created Date: 1975-09-09 Completed Date: 1975-09-09 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: SOUTH AFRICA |
Other Details:
|
Languages: eng Pagination: 789-92 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
African Americans* African Continental Ancestry Group Blood Vessels / pathology Female Follow-Up Studies Humans Inflammation / pathology Male Melanoma / mortality, pathology* Middle Aged Mitosis Pigmentation Pilot Projects Skin / pathology Skin Neoplasms / mortality, pathology* Skin Ulcer / pathology South Africa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nasotracheal intubation in acute laryngotracheobronchitis.
Next Document: Control of acute aortic dissection.