Document Detail


Pathology of abortion: chromosomal and genetic correlations.
MedLine Citation:
PMID:  2067518     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The examination of spontaneous abortion specimens is as important as doing perinatal autopsies or surgicals in today's practice of medicine. The results of the pathologist's examination assist obstetricians in specific follow-up of future pregnancies and geneticists in predicting the chances of specific developmental defects or repeat pregnancy loss. Without the information provided by the pathologist, the other specialists can offer no real assistance. More extensive use of cytogenetic analysis of placentas may help explain intrauterine fetal death in pregnancies with confined placental mosaicism, which complicates one to two percent of pregnancies. A brief review of morphologic and genetic differences between partial and complete moles emphasizes the disparate origins of these distantly related conditions.
Authors:
D K Kalousek
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Monographs in pathology     Volume:  -     ISSN:  0077-0922     ISO Abbreviation:  Monogr Pathol     Publication Date:  1991  
Date Detail:
Created Date:  1991-08-15     Completed Date:  1991-08-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0416716     Medline TA:  Monogr Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  228-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / genetics*,  pathology*
Chromosome Aberrations / pathology*
Chromosome Disorders
Female
Humans
Hydatidiform Mole / genetics,  pathology
Pregnancy
Uterine Neoplasms / genetics,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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