Document Detail

Pathological study of bronchospasms/tracheomalasia in patients with severe motor and intellectual disabilities.
MedLine Citation:
PMID:  15626546     Owner:  NLM     Status:  MEDLINE    
This report concerns two autopsy cases of severe motor and intellectual disabilities (SMID) who died of bronchospasms or tracheomalasia. One case had no anatomical change in the tracheal wall except for an endotracheal granuloma, while the other showed softening of the tracheal wall. Since patients with SMID have risk factors for bronchospasms and tracheomalasia, such as gastro-esophageal reflux, aspiration, and thoracic deformities, it is important that we suspect the possibility of these conditions, when we see the respiratory distress in cases of SMID.
Eiko Ohtsuka; Masaharu Hayashi; Kimiko Hamano; Satoko Kumada; Akira Uchiyama; Kiyoko Kurata; Makiko Osawa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Brain & development     Volume:  27     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-31     Completed Date:  2005-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  70-2     Citation Subset:  IM    
Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan.
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MeSH Terms
Brain / pathology*,  physiopathology
Bronchial Spasm / etiology*,  pathology,  physiopathology
Fatal Outcome
Gastroesophageal Reflux / etiology,  pathology,  physiopathology
Granuloma / pathology,  physiopathology
Mental Retardation / etiology,  pathology,  physiopathology
Movement Disorders / etiology,  pathology,  physiopathology
Nervous System Malformations / complications*,  pathology*,  physiopathology
Pneumonia, Aspiration / etiology,  pathology,  physiopathology
Respiratory Distress Syndrome, Adult / etiology,  pathology,  physiopathology
Trachea / pathology*,  physiopathology

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