Document Detail


Pathological fracture in acute osteomyelitis of long bones secondary to community-acquired methicillin-resistant Staphylococcus aureus: two cases and review of the literature.
MedLine Citation:
PMID:  17170628     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pathologic fracture is a rare complication of acute bacterial osteomyelitis in adults. Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has been increasingly reported in skin and soft tissue and systemic infections in children and adults, including many cases of osteomyelitis. We recently treated two adult patients with acute osteomyelitis of long bones secondary to CA-MRSA complicated by a pathologic fracture. In both patients, the primary source of dissemination to the bone was a skin and soft tissue infection. We speculate that virulence factors specific for CA-MRSA currently circulating in the United States may predispose to a complicated course of acute osteomyelitis.
Authors:
Michael S Gelfand; Kerry O Cleveland; Robert K Heck; Rekha Goswami
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  332     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-15     Completed Date:  2007-02-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  357-60     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Division of Infectious Diseases, University of Tennessee Health Science Center, Methodist University Hospital, Memphis, Tennessee 38104, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Bacterial Agents / therapeutic use
Community-Acquired Infections / complications*,  drug therapy,  microbiology
Female
Fractures, Spontaneous / etiology*
Humans
Methicillin Resistance*
Middle Aged
Osteomyelitis / complications*,  drug therapy,  microbiology
Staphylococcal Infections / complications*,  drug therapy,  microbiology*
Staphylococcus aureus* / drug effects
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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