Document Detail


Pathological changes in experimental saccular aneurysms in the carotid artery of the rat.
MedLine Citation:
PMID:  1675448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although the reason for development of saccular aneurysms in humans has still not been elucidated, the process might be observed and explained using a reproducible aneurysm model in vivo. In this paper, a sequential pathological study of the experimental saccular aneurysms was made. No additional influential factors were applied. At all stages of the development between the induction and 6 months, the histology of the aneurysm wall was similar to that of human aneurysms. The imbalance of the degeneration and regeneration processes during the development of these experimental aneurysms is discussed according to the pathological findings in different periods. Haemodynamic stress and different regenerative speeds in different arterial tissues must be responsible for the saccular aneurysm formation and growth.
Authors:
W Kamphorst; Y Z Gao; H A van Alphen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurological research     Volume:  13     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-07-17     Completed Date:  1991-07-17     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Free University Hospital, Amsterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Aneurysm / complications,  pathology*
Animals
Carotid Artery Diseases / pathology*
Carotid Artery Thrombosis / etiology
Disease Models, Animal
Female
Rats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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