Document Detail

Pathological analysis of hypertrophic cardiomyopathy simulating dilated cardiomyopathy.
MedLine Citation:
PMID:  8346707     Owner:  NLM     Status:  MEDLINE    
The pathomorphologic features of hypertrophic cardiomyopathy simulating dilated cardiomyopathy in the late stage (HCM-DCM) were compared with those of ordinary hypertrophic cardiomyopathy (HCM). Seven autopsied hearts with HCM-DCM and 11 with HCM were assessed quantitatively using an image analyzer. Unlike HCM, significant left ventricular enlargement and wall thinning were observed in HCM-DCM, and the percentage areas of massive fibrosis and disarray were significantly greater. In HCM-DCM, the disarray was distributed diffusely, whereas massive fibrosis was distributed more intensively in the ventricular septum and anterior wall than in the lateral and posterior wall. Narrowing of intramyocardial small arteries was observed more frequently in HCM-DCM, especially in the ventricular septum and anterior wall, than in HCM. These results suggest that the enlargement and wall thinning of the left ventricle in HCM-DCM are attributable to non-uniform progression of massive fibrosis, which is closely related to small-arterial lesions.
T Kawashima; Y Yokota; M Yokoyama; H Itoh
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta pathologica japonica     Volume:  43     ISSN:  0001-6632     ISO Abbreviation:  Acta Pathol. Jpn.     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-09-07     Completed Date:  1993-09-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372637     Medline TA:  Acta Pathol Jpn     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  304-12     Citation Subset:  IM    
First Department of Pathology, Kobe University School of Medicine, Japan.
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MeSH Terms
Arteries / pathology
Cardiomyopathy, Dilated / pathology*
Cardiomyopathy, Hypertrophic / pathology*
Coronary Vessels / pathology
Diagnosis, Differential
Middle Aged
Myocardium / pathology

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