| Pathological changes and immunoexpression of p63 gene in dental follicles of asymptomatic impacted lower third molars: an immunohistochemical study. | |
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MedLine Citation:
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PMID: 20485068 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to examine the pathologic changes and immunoexpressivity of p63 gene in dental follicles (DFs) of asymptomatic partially and completely impacted lower third molars. STUDY DESIGN: Clinical and radiologic examinations included 50 DFs with no signs of abnormal radiolucency (follicular space <2.5 mm), taken from 50 patients. RESULTS: Histopathologic examinations of the specimens revealed 47 normal dental follicular tissues, 1 ameloblastoma, and 2 dentigerous cysts. p63 Immunoexpressivity was stronger in the DFs of the group with completely impacted teeth (64%),than it was in the case of DFs of the group with partially impacted teeth (40%). CONCLUSIONS: Stronger p63 gene immunoexpression in the group with completely impacted teeth might be a consequence of bigger number of stem cells than it is in the case of the group with partially impacted teeth. This study also supports prophylactic removal of impacted teeth because of the development of pathologies associated with them. |
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Authors:
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Amila Brkić; Sevcihan Mutlu; Hülya Koçak-Berberoğlu; Vakur Olgaç |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of craniofacial surgery Volume: 21 ISSN: 1536-3732 ISO Abbreviation: J Craniofac Surg Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-20 Completed Date: 2010-09-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9010410 Medline TA: J Craniofac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 854-7 Citation Subset: D |
Affiliation:
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Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Istanbul University Capa, Istanbul, Turkey. amilabrkic@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Ameloblastoma / metabolism, pathology Dental Sac / metabolism, pathology*, radiography Dentigerous Cyst / metabolism, pathology Female Humans Immunoenzyme Techniques Jaw Neoplasms / metabolism, pathology, radiography Male Membrane Proteins / metabolism* Molar, Third / metabolism, pathology*, radiography Tooth, Impacted / metabolism, pathology*, radiography |
| Chemical | |
Reg. No./Substance:
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0/CKAP4 protein, human; 0/Membrane Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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