| Pathologic and laboratory correlation in microcephaly associated with prenatal cocaine exposure. | |
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MedLine Citation:
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PMID: 11408096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Authors report a case where cocaine abuse during pregnancy assessed by drug analysis at various site was associated with foetal microcephaly. Foetal pathologic findings revealed anomalies in neuronal migration and in the vascular architecture in the brain. Such anomalies might be the result of prolonged exposure to cocaine in utero, aggravated by the high concentration of cocaine metabolites in the amniotic fluid over a prolonged period. |
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Authors:
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A Kesrouani; C Fallet; E Vuillard; E Jacqz-Aigrain; O Sibony; J F Oury; P Blot; D Luton |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Early human development Volume: 63 ISSN: 0378-3782 ISO Abbreviation: Early Hum. Dev. Publication Date: 2001 Jul |
Date Detail:
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Created Date: 2001-06-15 Completed Date: 2001-07-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7708381 Medline TA: Early Hum Dev Country: Ireland |
Other Details:
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Languages: eng Pagination: 79-81 Citation Subset: IM |
Affiliation:
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Obstetrics and Gynaecology Department, Maternité de l'Hôpital Robert Debré, 48 Boulevard Sérurier, 75019 Paris, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Drug-Induced* Abortion, Eugenic Adult Brain / abnormalities, drug effects, metabolism Cocaine / adverse effects*, pharmacokinetics Cocaine-Related Disorders* Female Fetus / drug effects* Humans Maternal Exposure / adverse effects* Microcephaly / chemically induced* Pregnancy Pregnancy Complications Tissue Distribution |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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