Document Detail

Pathologic findings associated with invasive EEG monitoring for medically intractable epilepsy.
MedLine Citation:
PMID:  23010704     Owner:  NLM     Status:  In-Data-Review    
Invasive electroencephalography (EEG) monitoring is often needed for presurgical evaluation in patients with medically intractable epilepsy (MIE). This study retrospectively reviews the pathologic changes associated with EEG monitoring. Two hundred twenty-six patients who underwent invasive monitoring (53.5% males; mean age, 29.8 years) and 55 controls without EEG monitoring (52.7% males; mean age, 25.6 years) were evaluated. Median length of invasive EEG monitoring was 7.0 days. Compared with controls, patients who were monitored had more pathologic changes related to invasive EEG monitoring (n = 171 [75.7%] vs n = 12 [21.8%]; P < .0001) including meningeal or parenchymal chronic inflammation (n = 128 [56.4%] vs n = 11 [20.4%]; P < .0001) and acute contusion and/or acute/subacute infarct (n = 110 [48.5%] vs n = 0; P < .0001). Histologic evidence of pathologic changes typically associated with invasive monitoring and/or craniotomy occurred in 76% of our patients with invasive monitoring compared with 19% in patients without prior invasive EEG evaluation. The most common pathologic changes related to invasive monitoring were chronic inflammation and contusion/infarct.
Joanna S Fong; Andreas V Alexopoulos; William E Bingaman; Jorge Gonzalez-Martinez; Richard A Prayson
Related Documents :
24908094 - Determination of homocysteine in cerebrospinal fluid as an indicator for surgery treatm...
23306064 - Fronto-striatal atrophy correlates of inhibitory dysfunction in parkinson's disease ver...
24741564 - Serum 25-hydroxyvitamin d deficiency in ischemic stroke and subtypes in indian patients.
23011084 - Soluble cd163 serum levels are elevated and correlated with il-12 and cxcl10 in patient...
21677034 - Premature ovarian failure in patients with autoimmune addison's disease: clinical, gene...
1681944 - Patterns of manual dominance in patients with neuroleptic-induced movement disorders.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  138     ISSN:  1943-7722     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  506-10     Citation Subset:  AIM; IM    
Cleveland Clinic Main Campus, Mail Code L25, 9500 Euclid Ave, Cleveland, OH 44195;
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pathology Consultation on Transfusion-Related Acute Lung Injury (TRALI).
Next Document:  Decreased androgen receptor expression is associated with distant metastases in patients with androg...